Diabetes

Diabetes is one of the most common chronic conditions in children. Rates of type 1 diabetes and type 2 diabetes among children and youth have been on the rise globally. Canada has one of the highest incidence rates of type 1 diabetes for children under 14 years of age.

The CHEO Diabetes team is always striving to improve the care that we provide to the over 900 children and youth that we follow.  One way that we improve care for our patients is through research. The clinical research program at CHEO focuses on several different aspects of diabetes including, but not limited to:

  • Clinical trials to prevent type 1 diabetes
  • Better understanding of the natural history of diabetes and trends in management over time
  • How the use of technology such as pump therapy and continuous glucose monitoring can optimize glucose control and quality of life
  • Improving care delivery through improved access (e.g. using technology), educational needs, and addressing social determinants of health
  • Transition from pediatric to adult diabetes care
  • Improving overall wellness and quality of life for children and youth with diabetes
  • Improving complications in adolescents with type 2 diabetes

Current Projects:

Sweet Study:

SWEET Minor Mod 2 Recruitment poster

ADDAM Study:

ADDAM recruitment poster

iCARE Study:

iCARE recruitment poster

Related News

Research Projects

  1. Social determinants of health linked with patient portal use in pediatric diabetes

    12/04/2022

  2. Patient and family perspective of a Pre-Transition Visit in a pediatric tertiary care diabetes clinic

    31/01/2022

    Overall, we found that both patients and their families had high levels of satisfaction with the Pre-T Visit which reinforced this as a good use of resources (ie, patient, administrative and educator time) in our clinic, with respect to the patient experience. These findings were consistent across patients despite differences in age, gender, diabetes duration and A1C. Furthermore, patients reported high levels of engagement/participation in the visit.

  3. Role of Sex and Gender in Access to Care and Cardiovascular Complications of Individuals with Diabetes Mellitus

    01/10/2021

    Country-specific gender related factors and gender disparity must be targeted for improving health status and access to care of patients with DM.

  4. Psychiatric disorders in emerging adults with diabetes transitioning to adult care: a retrospective cohort study

    12/02/2021

    Prolonged gaps in care during transfer to adult care are common and may be associated with increased psychiatric disorder risk. Developmental factors associated with adolescence and emerging adulthood may further amplify this risk.

  5. Timing of CGM initiation in pediatric diabetes: The CGM TIME Trial

    23/10/2020

    CGM adherence was higher after 6 months when initiated at same time as pump therapy compared to starting CGM 6 months after pump therapy. Greater CGM adherence was associated with improved HbA1c.

  6. The impact of limited and strategic blood glucose monitoring on metabolic control in a type 1 diabetes clinic in Central India

    01/05/2020

    This study assessed whether the use of two SMBG tests per day improves glycemic control, measured by a change in HbA1c, in youth with T1D followed at the DREAM Trust (DT) in Nagpur, India.

  7. Effect of Hydrolyzed Infant Formula vs Conventional Formula on Risk of Type 1 Diabetes: The TRIGR Randomized Clinical Trial

    01/01/2018

    Among infants at risk for type 1 diabetes, weaning to a hydrolyzed formula compared with a conventional formula did not reduce the cumulative incidence of type 1 diabetes after median follow-up for 11.5 years. These findings do not support a need to revise the dietary recommendations for infants at risk for type 1 diabetes.

  8. Management of Type 1 diabetes in a limited resource context: A study of the diabetes research education and management trust model in Nagpur, Central India

    04/10/2017

    The DT charitable programme overcomes social status, gender inequalities and experience of social stigma to provide life-saving treatment to children with T1D in central India.

  9. Social Determinants of Health on Glycemic Control in Pediatric Type 1 Diabetes

    03/04/2013

    Measures of the SDH comprising Material and Social Deprivation were significantly associated with suboptimal glycemic control in our pediatric T1D cohort. Use of insulin pump therapy also predicted A1C and may have a moderating effect on these relationships.

Researchers

  1. Alexandra Ahmet

    Investigator, CHEO RI

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  2. Jean-Philippe Chaput

    Senior Scientist, CHEO Research Institute

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  3. Khaled El Emam

    Senior Scientist, CHEO Research Institute Professor, Faculty of Medicine, University of Ottawa

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  4. Ellen Goldbloom

    Investigator, CHEO Research Institute

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  5. Margaret Lawson

    Senior Scientist, CHEO Research Institute

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  6. Alex MacKenzie

    Senior Scientist, CHEO Research Institute

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  7. Marie-Eve Robinson

    Investigator, CHEO Research Institute

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  8. Caroline Zuijdwijk

    Investigator, CHEO Research Institute

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Family Leaders

  1. Adeseun Ilori

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  2. Andrew McVey

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  3. Bleadon Anderson

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  4. Laurie Woodward

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  5. Madeleine Latour

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  6. Mariann Michael

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  7. Samantha Bellefeuille

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  8. Spencer Warren

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