CHEO & OHSN REB Harmonization Agreement

CHEO & OHSN REB Harmonization Agreement

In 2019 the CHEO and OHSN REB’s entered into an institutional agreement, in order to streamline the ethics review of studies happening at both CHEO and the Ottawa Hospital.

What does this mean for researchers?

Studies falling under the jurisdiction of both CHEO REB and OHSN REB (i.e., due to Investigator affiliations and/or study activity at both sites) will no longer require two separate ethics applications.

CHEO and OHSN REB will work collaboratively to review and approve the research studies using one ethics application. There will be a single Research Ethics Board of record.

What is the process for requesting research studies be reviewed under this agreement?

Study teams must complete a REDCap Survey: TOH & CHEO REB Harmonization

The Survey will be reviewed to determine the ethics review system to be used for the life of the study.

The study team will receive a notification indicating which REB will be the REB of Record and what system should be used to submit the ethics application and study registration.

The study team will receive research ethics review and decision making from a single REB (OHSN or CHEO) for the life of the study.

The study team must also obtain Institutional approval at each institution (OHRI or OHIRC and CHEO/CHEO RI) is required prior to starting the study.


If in addition to CHEO and or TOH/UOHI, the research will be conducted at multiple sites in Ontario who are participating sites in Clinical Trials Ontario (CTO), the research study should be submitted through CTO Stream.


If you have any questions regarding this process, please contact the REB office.