Discoveries

Averageing over 500 scientific publications a year, the CHEO Research Institute knows that patients, families, and the comunity need to be able to access our findings in order to educate themselves on the breakthroughs in pediatrac patient care Research.

  1. Attitudes toward physical activity as a treatment component for adolescents with anorexia nervosa: An exploratory qualitative study of patient perceptions

    13/11/2021

    This study allows for the inclusion of patient voices in the conversation surrounding the role of physical activity in AN treatment.

  2. Gender differences in physical activity and sedentary behavior: results from over 200,000 Latin-American children and adolescents

    12/08/2021

    In conclusion, gender differences in the compliance with physical activity guidelines and the <3 hours recreational sedentary behavior cut-point are evident among children and adolescents from Latin-American countries, with boys being more active than girls.

  3. Epidemiologic and clinical characteristics of multisystem inflammatory syndrome in adults: a rapid review

    04/08/2021

    Further studies to improve our understanding of pathogenesis of MIS-A will help improve treatment decisions and prevent sequelae and death.

  4. High-dose AraC is Essential for the Treatment of ML-DS Independent of Post-Induction MRD: Results of COG AAML1531

    28/07/2021

  5. When Should Bisphosphonates Be Used in Children with Chronic Illness Osteoporosis?

    19/06/2021

    The decision to treat a child with a bisphosphonate hinges on distinguishing bone fragility from typical childhood fractures, and determining the potential for medication-unassisted recovery following an osteoporotic fragility fracture. While improvements in BMD are a well-known sign of recovery, restitution of bone structure is also a key indicator of recuperation, one that is unique to childhood, and that plays a pivotal role in the decision to intervene or not.

  6. Vitamin D supplementation for children with cancer: a systematic review and consensus recommendations

    08/06/2021

    Further research is needed; until then, we recommend dietary vitamin D/calcium intake in keeping with standard national guidelines, and periodic 25OHD monitoring to detect levels <20 ng/ml. Vitamin D/calcium supplementation is recommended in children with low levels, to maintain levels ≥20 ng/ml year-long.

  7. The impact of COVID-19 on adolescents with eating disorders: a cohort study

    04/06/2021

    Further research is required to better understand the impact of the pandemic on the clinical course and outcomes of EDs in adolescents.

  8. Aerosol SARS-CoV-2 in hospitals and long-term care homes during the COVID-19 pandemic

    04/06/2021

    Although a subset of aerosol samples exhibited detectable SARS-CoV-2 RNA at low titres, the presence of viable SARS-CoV-2 virus in aerosols appears to be infrequent at >2m distance.