Research Projects

Averageing over 500 scientific publications a year, the CHEO Research Institute knows that patients, families, and the comunity need to be able to access our findings in order to educate themselves on the breakthroughs in pediatrac patient care Research.

  1. World Health Organization 2020 guidelines on physical activity and sedentary behaviour

    26/11/2020

    These guidelines should be used to inform national health policies aligned with the WHO Global Action Plan on Physical Activity 2018-2030 and to strengthen surveillance systems that track progress towards national and global targets.

  2. Advancing the global physical activity agenda: recommendations for future research by the 2020 WHO physical activity and sedentary behavior guidelines development group

    26/11/2020

    Although the 2020 WHO Guidelines for Physical Activity and Sedentary Behavior were informed by the most up-to-date research on the health effects of physical activity and sedentary time, there is still substantial work to be done in advancing the global physical activity agenda.

  3. 2020 WHO guidelines on physical activity and sedentary behaviour for children and adolescents aged 5-17 years: summary of the evidence

    26/11/2020

    Addressing the identified research gaps will better inform guideline recommendations in children and adolescents, and future work should aim to prioritize these areas of research. In the meantime, investment and leadership is needed to scale up known effective policies and programs aimed at increasing activity in children and adolescents.

  4. Effect of Nebulized Magnesium vs Placebo Added to Albuterol on Hospitalization Among Children With Refractory Acute Asthma Treated in the Emergency Department: A Randomized Clinical Trial

    24/11/2020

    Among children with refractory acute asthma in the emergency department, nebulized magnesium with albuterol, compared with placebo with albuterol, did not significantly decrease the hospitalization rate for asthma within 24 hours. The findings do not support use of nebulized magnesium with albuterol among children with refractory acute asthma.

  5. Evaluating Identity Disclosure Risk in Fully Synthetic Health Data: Model Development and Validation

    11/11/2020

    We have presented a comprehensive identity disclosure risk model for fully synthetic data. The results for this synthesis method on 2 datasets demonstrate that synthesis can reduce meaningful identity disclosure risks considerably. The risk model can be applied in the future to evaluate the privacy of fully synthetic data.

  6. Canadian Association of Radiologists White Paper on De-Identification of Medical Imaging: Part 1, General Principles

    03/11/2020

    The application of AI algorithms in radiology requires access to large data sets containing PHI. The CAR AI Ethical and Legal standing committee published Part 2 of this guide to provide a practical approach to de-identification in the context of the current Canadian health care landscape. This article discussed the practical application of protecting patient data in the reality of our current Canadian clinical landscape. The strengths and weaknesses of de-identification approaches were outlined, along with the complexities of protecting patients’ medical imaging data, the possible de-identification software tools available, some common mistakes made by research and development teams, and perspectives on future directions.

  7. Abnormal placental pathological findings and adverse clinical outcomes of oocyte donation

    02/11/2020

    Placental pathology reflecting dysregulated immune processes and vasculopathy is associated with oocyte donation.

  8. Advances in Bone Assessment Methods in Children

    02/11/2020

    INTRODUCTION Pediatric bone diseases present with a variety of signs and symptoms. Although some diagnoses may be straightforward based on history and physical examination, other presentations require more extensive bone assessments. In addition, clinical followup, research studies, and drug trials are predicated on strong bone health assessment.