Alex MacKenzie is an attending pediatrician at the Children’s Hospital of Eastern Ontario(CHEO) in Ottawa, Canada and has served as the CEO and Science Director of the CHEOResearch Institute as well as Vice President of Research for both CHEO and Canada’s federalgenomic research funding agency, Genome Canada. In addition to being a founding scientist ofthe AeGera biotech company, Dr. MacKenzie’s laboratory has conducted translational researchon the rare pediatric disorder spinal muscular atrophy over the past 25 years; in recent years ithas broadened its focus through the enhanced Care for Rare project to search for therapies for alarger number of rare genetic diseases.
SARS-CoV-2 Protein in Wastewater Mirrors COVID-19 Prevalence
Here, we demonstrate the presence of SARS-CoV-2 structural proteins in wastewater using traditional immunoblotting and quantitate them from wastewater solids using an immuno-linked PCR method called Multiplex Paired-antibody Amplified Detection (MPAD). In this longitudinal study, we corrected for stochastic variability inherent to wastewater-based epidemiology using multiple fecal content protein biomarkers.
Quantitative analysis of SARS-CoV-2 RNA from wastewater solids in communities with low COVID-19 incidence and prevalence
Can we find COVID-19 markers in the wastewater that will help predict outbreaks?
Researching COVID-19 Community Markers in Wastewater
This is an active study.