Karine Khatchadourian

Investigator, CHEO Research Institute

Dr Khatchadourian completed medical school and a pediatrics residency at the University of Montreal. She then completed her training in pediatric endocrinology at the University of British Columbia along with a Master’s in health sciences.
She is a pediatric endocrinologist at CHEO and an Assistant Professor of Pediatrics at the University of Ottawa.

Her research interests include examining  bone health in transgender and nonbinary youth on puberty blockers and gender affirming hormones, collaborative work with investigators assessing health outcomes in the transgender population using health administrative data and patient reported outcomes. She also has an interest in growth hormone studies for endocrine conditions. She is the principal investigator of an RCT comparing the effect and safety of once weekly dosing of somapacitan with daily Norditopin® as well as evaluating long-term safety of somapacitan in children with Turner syndrome.

Research Projects

  1. Teaching Adolescents With Type 1 Diabetes Self-Compassion (TADS) to Reduce Diabetes Distress: Protocol for a Randomized Controlled Trial

    26/12/2023

    This randomized controlled trial aims to evaluate whether a web‑based mindful self‑compassion program can reduce diabetes distress and related mental health challenges among adolescents living with type 1 diabetes. By comparing the intervention with standard care, the study will assess impacts on emotional well‑being, diabetes‑related behaviors, and glycemic control over 12 months. The findings are expected to inform scalable psychological supports that help adolescents better manage the emotional demands of living with type 1 diabetes.

  2. Control-IQ Technology Positively Impacts Patient Reported Outcome Measures and Glycemic Control in Youth with Type 1 Diabetes in a Real-World Setting

    12/04/2023

    Initiation of Control-IQ technology in a real-world setting significantly reduced the impact of diabetes on daily life while simultaneously improving glycemic control

  3. Pubertal Suppression, Bone Mass and Body Composition in Youth with Gender Dysphoria

    01/10/2021

    The majority of transgender youth had vitamin D insufficiency or deficiency with baseline status associated with bone mineral density. Vitamin D supplementation should be considered for all youth with GD.