Endocrinology

Endocrinology is the area of medicine that relates to the endocrine system, which is the system that controls hormones. It’s characterized by the following types of symptoms or diseases:

  • Growth and/or puberty disorders
  • Thyroid disorders
  • Hypoglycaemia of suspected endocrine origin (not metabolics)
  • Other known or suspected endocrine problems of childhood or adolescence

Investigators at the CHEO Research Institute are currently studying new options for children who don’t have enough growth hormone in their bodies.

Research Projects

  1. Motivational Interviewing and the Use of Psychological Services Among Youth With Chronic

    01/10/2021

    All specialized pediatricians have a role to play in ensuring that at-risk youth with CMCs receive the psychiatric support they need.

  2. Pubertal Suppression, Bone Mass and Body Composition in Youth with Gender Dysphoria

    01/10/2021

    The majority of transgender youth had vitamin D insufficiency or deficiency with baseline status associated with bone mineral density. Vitamin D supplementation should be considered for all youth with GD.

  3. Intravenous zoledronic acid versus placebo in children with glucocorticoid-induced osteoporosis: A randomized, double-blind, multi-national phase 3 trial

    06/07/2021

    LSBMDZ increased significantly on ZA compared with placebo over 1 year in children with GIO. Most AEs occurred after the first infusion.

  4. When Should Bisphosphonates Be Used in Children with Chronic Illness Osteoporosis?

    19/06/2021

    The decision to treat a child with a bisphosphonate hinges on distinguishing bone fragility from typical childhood fractures, and determining the potential for medication-unassisted recovery following an osteoporotic fragility fracture. While improvements in BMD are a well-known sign of recovery, restitution of bone structure is also a key indicator of recuperation, one that is unique to childhood, and that plays a pivotal role in the decision to intervene or not.

  5. The Accuracy of Incident Vertebral Fracture Detection in Children Using Targeted Case-Finding Approaches

    30/03/2021

    These results provide guidance for targeting spine radiography in children at risk for IVF.

  6. Advances in Bone Assessment Methods in Children

    02/11/2020

    INTRODUCTION Pediatric bone diseases present with a variety of signs and symptoms. Although some diagnoses may be straightforward based on history and physical examination, other presentations require more extensive bone assessments. In addition, clinical followup, research studies, and drug trials are predicated on strong bone health assessment.

  7. Timing of CGM initiation in pediatric diabetes: The CGM TIME Trial

    23/10/2020

    CGM adherence was higher after 6 months when initiated at same time as pump therapy compared to starting CGM 6 months after pump therapy. Greater CGM adherence was associated with improved HbA1c.

  8. Where Have the Periods Gone? The Evaluation and Management of Functional Hypothalamic Amenorrhea

    01/01/2020

    Functional hypothalamic amenorrhea (FHA) is a common cause of amenorrhea in adolescent girls.

  9. Adrenal suppression from glucocorticoids: preventing an iatrogenic cause of morbidity and mortality in children

    29/10/2019

    The intent of this review is to draw attention to this important entity and to allow the reader to create an informed and practical approach to the management of their patients at risk.

  10. Comprehensive Curriculum in Pediatric and Adolescent Gynecology for Postgraduate Trainees in Obstetrics/Gynecology, Pediatrics, and Adolescent Medicine

    01/10/2019

    Providing educators with a comprehensive document to be used in post-graduate medical education.

  11. Comparison of the diagnostic performance of the 2017 ACR TI-RADS guideline to the Kwak guideline in children with thyroid nodules

    01/06/2019

    Both the Kwak-TI-RADS and ACR TI-RADS guidelines provide moderate malignancy risk stratification for thyroid nodules in the pediatric population, with better inter-rater agreement for the ACR TI-RADS guideline. Further work to adjust the recommendations for pediatric patients is necessary.

Researchers

  1. Alexandra Ahmet

    Investigator, CHEO RI

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  2. Annick Buchholz

    Investigator, CHEO Research Institute

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  3. Tania Dumont

    Investigaor, CHEO Research Institute

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  4. Kerri Highmore

    Investigator, CHEO Research Institute

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  5. Tom Kovesi

    Investigator, CHEO Research Institute

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  6. Margaret Lawson

    Senior Scientist, CHEO Research Institute

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  7. Elka Miller

    Investigator, CHEO Research Institute

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  8. Marie-Eve Robinson

    Investigator, CHEO Research Institute

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  9. Leanne Ward

    Senior Scientist, CHEO Research Institute

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  10. Caroline Zuijdwijk

    Investigator, CHEO Research Institute

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