Infectious Disease

The team’s vision is to conduct and disseminate high-quality clinical research in infectious diseases of children and youth in collaboration with local, provincial and national partners. The research focuses on the prevention, diagnosis, management and impact of infectious diseases in children and youth with specific attention to vulnerable populations.


  1. Vaccination/immunizations
  2. Primary and acquired immune deficiencies/HIV
  3. Molecular diagnostics
  4. Health care associated infections
  5. New Canadians (immigrants, refugees, internationally adopted)
  6. Evidence-based health advocacy

Related News

Research Projects

  1. Combined influence of practice guidelines and prospective audit and feedback stewardship on antimicrobial treatment of community-acquired pneumonia and empyema in children: 2012 to 2016


    Use of AAP should also be strongly considered in patients with effusions (even if no pathogen is identified), as clinical outcome appears similar to patients treated with broad-spectrum antimicrobials.

  2. CpG Methylation in TGFβ1 and IL-6 Genes as Surrogate Biomarkers for Diagnosis of IBD in Children


    We found that CpG methylation in the promoter of the TGFβ1 gene has high discriminative power for identifying CD and UC and could serve as an important diagnostic marker

  3. Epidemiology and Clinical Outcomes of Hospitalizations for Acute Respiratory or Febrile Illness and Laboratory-Confirmed Influenza Among Pregnant Women During Six Influenza Seasons, 2010–2016


    Our findings characterize seasonal influenza hospitalizations among pregnant women and can inform assessments of the public health and economic impact of seasonal influenza on pregnant women.

  4. Health outcomes of young children born to mothers who received 2009 pandemic H1N1 influenza vaccination during pregnancy: retrospective cohort study


    Pregnant women are considered to be at high risk for serious illness due to influenza related mortality and morbidity documented during influenza pandemics and seasonal epidemics. No associations were observed between exposure to pH1N1 influenza vaccine during pregnancy and most five year pediatric health outcomes.


  1. Melanie Buba

    Investigator, CHEO Research Institute

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  2. Deshayne Fell

    Scientist, CHEO Research Institute

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  3. David Mack

    Senior Scientist, CHEO Research Institute

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  4. Dayre McNally

    Scientist, CHEO Research Institute

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Family Leaders

  1. Laurie Woodward

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  2. Samantha Bellefeuille

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