Dr. Zemek is a pediatric emergency researcher with experience in multicenter studies, randomized controlled trials, and systematic reviews. He has research experience in pediatric concussion, including systematic reviews, guideline development, health administrative datasets, derivation and validation of clinical prediction rules, and interventional trials. Dr. Zemek is leading a national research program on pediatric concussion, through which he conducted the largest concussion study in the world to-date examining the predictors for Persistent Post-Concussion Symptoms in children suffering a concussion (5P study). He also led an international team for the development of guidelines for the management of pediatric concussion.
Dr. Zemek co-leads the Living Guideline for Diagnosing and Managing Pediatric Concussion, a project that is supported by the Ontario Neurotrauma Foundation. Information for patients and families on these guidelines can be found here, and Clinical Recommendations for health care professionals providing care for pediatric patients with a suspected concussion can be found here.
Through Pediatric Emergency Research Canada (PERC), Dr. Zemek is also an investigator on multiple asthma studies and mental health studies of children presenting to the Emergency Department
Effect of Nebulized Magnesium vs Placebo Added to Albuterol on Hospitalization Among Children With Refractory Acute Asthma Treated in the Emergency Department: A Randomized Clinical Trial
Among children with refractory acute asthma in the emergency department, nebulized magnesium with albuterol, compared with placebo with albuterol, did not significantly decrease the hospitalization rate for asthma within 24 hours. The findings do not support use of nebulized magnesium with albuterol among children with refractory acute asthma.
Symptom Burden, School Function, and Physical Activity One-Year Following Pediatric Concussion
Most youth are symptom-free and fully recovered one year following concussion. Some children with repeat concussion have worse outcomes and have delays in returning to normal school routines and sport.
Early versus delayed emergency department presentation following mild Traumatic Brain Injury and the presence of symptom at 1, 4 and 12 weeks in children
We evaluated the association between timing of presentation and postconcussive symptoms (PCS) at 1, 4 and 12 weeks after injury.
Health outcomes associated with emergency department visits by adolescents for self-harm: a propensity-matched cohort study
Adolescents with emergency department visits for self-harm have higher rates of mortality, suicide and recurrent self-harm, as well as higher health care costs, than matched controls.
Paediatric acute lymphadenitis: Emergency department management and clinical course
The vast majority of children with acute lymphadenitis were managed with outpatient oral antibiotics and did not require return emergency department visits or surgical drainage.