Sleep disordered breathing (SDB) is associated with many childhood diseases. Children with obesity or neuromuscular disease, for example, may develop hypoventilation from weak or overloaded respiratory muscles, compromising airway patency and/or gas exchange during sleep. Children with mood disorders and hypertension may also have a higher incidence of disordered sleep compared to others in the general population. The research agenda of this team is to determine the prevalence of sleep disordered breathing and assistive technologies in chronic disease states, to study diagnostic tools and predictors of sleep-disordered breathing, and to evaluate the benefits and consequences of treatment from a multi-disciplinary perspective. Treatment of the sleep disordered breathing alongside the underlying condition must be considered in development of a management plan and the consequences and benefits of this treatment then can thus be better understood.
Insulin Resistance and Hypertension in Obese Youth With Sleep-Disordered Breathing Treated With Positive Airway Pressure: A Prospective Multicenter Study
In youth with obesity and SDB, metabolic dysfunction and hypertension were highly prevalent. Larger, longer-term studies are needed to determine whether PAP improves cardiometabolic outcomes in obese youth.
Does Neck-to-Waist Ratio Predict Obstructive Sleep Apnea in Children?
Neck-to-waist ratio, an index of body fat distribution, predicts OSA in older children and youth, especially in those who were overweight/obese.