The legalization of cannabis in Canada has opened up a new area of research. Or scientific teams are investigating the benefits of different components of cannabis, through the careful lens of youth care.

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Research Projects

  1. Potential Benefit of Add-on Δ9-Tetrahydrocannabinol in Pediatric Drug-Resistant Epilepsy: A Case Series


    Based on our experiences and reports in the literature, we propose that, in patients who fail management with an initial trial of high-dose CBD-focused therapy, there may be a role for add-on THC-focused formulations.

  2. Maternal cannabis use in pregnancy and child neurodevelopmental outcomes


    With the legalization of recreational cannabis in many jurisdictions, there is concern about potentially adverse childhood outcomes related to prenatal exposure.

  3. Cannabis treatment in children with epilepsy: Practices of Canadian neurologists


    The majority of Canadian pediatric neurologists consider using cannabis as a treatment for epilepsy in children. With many gaps in evidence and high patient-driven demand for cannabis therapy, this survey provides immediate information from the “wisdom of the crowd,” to aid neurologists until further evidence is available.

  4. Cannabis use for therapeutic purposes by children and youth at a tertiary teaching hospital in Canada: A retrospective chart review


    Medically supervised cannabis use occurred most often in patients with intractable or refractory seizures. According to these data, seizure response is variable, and initial decreases may be transient for pediatric patients using cannabis. To ensure greater consistency and rigour in the conduct of prospective research and thus to generate better-quality research on the therapeutic effects of medical cannabis, development of a standardized care record is needed.

  5. Association Between Self-reported Prenatal Cannabis Use and Maternal, Perinatal, and Neonatal Outcomes


    Among pregnant women in Ontario, Canada, reported cannabis use was significantly associated with an increased risk of preterm birth.

  6. Trends and correlates of cannabis use in pregnancy: a population-based study in Ontario, Canada from 2012 to 2017


    Cannabis use in pregnancy has increased since 2012 in Ontario and was reported in about 2% of pregnancies in 2017.


  1. Melanie Bechard

    Investigator, CHEO Research Institute

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  2. Daniel Corsi

    Scientist, CHEO Research Institute

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  3. Deshayne Fell

    Scientist, CHEO Research Institute

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  4. Erick Sell

    Investigator, CHEO Research Institute

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  5. Christina Vadeboncoeur

    Investigator, CHEO Research Institute

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  6. Richard Webster

    Investigator, CHEO Research Institute

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