Andrée-Anne Ledoux

Scientist CHEO Research Institute

Dr. Ledoux is a Scientist at the CHEO Research Institute and Assistant Professor for the Cellular Molecular Medicine Department at University of Ottawa. Dr. Ledoux has a PhD in Experimental Psychology and Behavioural Neuroscience.

Dr. Ledoux and her team is interested in developing and testing management protocols that target neuronal repair in the hopes of reducing the risk of persistent post-concussive symptoms, reducing the recovery period, and promoting resiliency and neural protection in pediatric concussion. She is interested in identifying recovery neural correlates that can be used as recovery biomarkers in concussion and investigating how behavioural treatments can modify these biomarkers. She is currently investigating the acute and subacute clinical, neuropsychological and neurophysiological recovery processes of two different behavioural management protocols: early return to physical activity and mindfulness-based intervention with MRI. Given the extensive brain maturation and significant functional development that occurs throughout childhood in addition to the sex differences that exist throughout development, she also explores age and sex-based differences in all of her concussion-related studies. Together with a multidisciplinary approach, cutting edge techniques and national/international collaborations she hopes to reduce the impact of concussion in children and adolescents and their family.

Related News

Research Projects

  1. Risk of Mental Health Problems in Children and Youth Following Concussion: A Population-Based Retrospective Cohort Study


    Among children and youths aged 5 to 18 years, concussion was associated with an increased risk of mental health issues, psychiatric hospitalization, and self-harm compared with children and youths with an orthopedic injury.

  2. Is early activity resumption after paediatric concussion safe and does it reduce symptom burden at 2 weeks post injury? The Pediatric Concussion Assessment of Rest and Exertion (PedCARE) multicentre randomised clinical trial


  3. Sex-based differences in symptoms with mouthguard use following pediatric sport-related concussion


    Athletes are still encouraged to wear mouthguards during sports because overwhelming evidence supports their use in preventing dental injuries.

  4. Association between pre-injury symptoms and post-concussive symptoms at 4-weeks in youth and adolescents


    Providers should consider preinjury symptoms to inform prognosis and recovery management.

  5. Symptom Burden, School Function, and Physical Activity One-Year Following Pediatric Concussion


    Most youth are symptom-free and fully recovered one year following concussion. Some children with repeat concussion have worse outcomes and have delays in returning to normal school routines and sport.