Study contact: [email protected]
Study contact full name: Doaa Abdelfattah
Research Area: Cancer
Who to contact regarding participation: Dr. Donna Johnston (Site PI) Doaa Abdelfattah (Research Coordinator)
What is the study about?
Will taking metformin improve thinking skills, especially memory and processing speed, in children and young adults treated for a brain tumour?
Who can participate?
We are looking for children and young adults 7-21 years of age who have finished primary therapy for a brain tumour, have an IQ more than 60 on a screening test, able to swallow tablets either whole, crushed or via a feeding tube, and speak English
What’s involved?
- 5 in-person visits and 4 check-in phone calls or virtual visits. In-person visits can include:
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Physical and Neurological Exam (1 hour x 4 visits)
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IQ and Thinking Tests (1-2.5 hours x 4 visits)
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Blood Draw (30 minutes x 2 visits)
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Health Questionnaire (5 minutes x 3 visits)
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Getting tablets that will be taken at home (5 minutes x 1 visit)
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Magnetic Resonance Imaging (MRI) scan [no contrast] (45-60 minutes x 3 visits)
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- Taking tablets 1-2 times a day for 16 weeks and keeping a medication diary
- All visits will occur across 41 weeks
Are there benefits to participating?
There are no direct benefits to you for participating in this research. Participants may be given a volunteer certificate and a summary of their cognitive testing results
Version date: March 5, 2025