Ciarán Duffy

Emeritus Scientist, CHEO Research Institute

Dr. Ciarán Duffy graduated from medical school at University College, Dublin in 1979 and then completed a paediatric residency at The Children’s Hospital of Western Ontario, London; a fellowship in paediatric rheumatology at The Hospital for Sick Children, Toronto; and a Master’s degree in Clinical Epidemiology at McMaster University, Hamilton. He practiced for more than 20 years in Montreal and was Professor and Associate Chairman of the Department of Paediatrics at McGill University and Director of the Division of Rheumatology and Associate Paediatrician-in-Chief at The Montreal Children’s Hospital. He relocated to Ottawa in April 2011 to assume the role of Professor and Chairman, Department of Paediatrics, University of Ottawa, and Chief of Paediatrics, Children’s Hospital of Eastern Ontario.

Research Projects

  1. Prospective Determination of the Incidence and Risk Factors of New-Onset Uveitis in Juvenile Idiopathic Arthritis: The Research in Arthritis in Canadian Children Emphasizing Outcomes Cohort


    Identification of the incidence of juvenile idiopathic arthritis (JIA)-associated uveitis and its risk factors is essential to optimize early detection. Data from the Research in Arthritis in Canadian Children Emphasizing Outcomes inception cohort were used to estimate the annual incidence of new-onset uveitis following JIA diagnosis and to identify associated risk factors.

  2. Health-Related Quality of Life in an InceptionCohort of Children With Juvenile IdiopathicArthritis: A Longitudinal Analysis


    Improvement in HRQoL is slower than for disease activity, pain, and disability. Improvement of a mea- sure based on respondents’ preferences (HRQoML) is more rapid than that of a standardized measure (JAQQ). Higher disease activity at diagnosis heralds an unfavorable HRQoL trajectory.

  3. The risk and nature of flares in juvenile idiopathic arthritis: results from the ReACCh-Out cohort


    In this real-practice JIA cohort, flares were frequent, usually involved a few swollen joints for an average of 6 months and 60% led to treatment intensification. Children with a severe disease course had an increased risk of flare.