1 00:00:00,125 --> 00:00:01,751 I was born premature. 2 00:00:01,751 --> 00:00:04,754 What impact could that have on the structure of my lungs, 3 00:00:05,005 --> 00:00:08,216 my breathing when I sleep, and my physical activity levels? 4 00:00:08,299 --> 00:00:11,511 Would having an MRI of my lungs help answer this? 5 00:00:12,262 --> 00:00:13,805 Thank you for the question. 6 00:00:13,805 --> 00:00:17,058 Children who are born extremely preterm, particularly those 7 00:00:17,058 --> 00:00:18,935 who have bronchopulmonary dysplasia 8 00:00:18,935 --> 00:00:22,814 or BPD, are at risk of having persisting lung abnormalities. 9 00:00:23,148 --> 00:00:24,357 This is because if you're born 10 00:00:24,357 --> 00:00:27,902 extremely preterm, your lungs have not yet had a chance to fully develop. 11 00:00:28,778 --> 00:00:31,031 Our study looked at whether MRI of the lungs, 12 00:00:31,031 --> 00:00:34,200 a way of taking pictures of the lungs would help 13 00:00:34,200 --> 00:00:38,413 to define those pulmonary abnormalities and look for differences 14 00:00:38,413 --> 00:00:41,499 between those children who had BPD and those who didn't. 15 00:00:42,167 --> 00:00:44,085 We recruited 35 children 16 00:00:44,085 --> 00:00:47,505 who are school aged between the ages of seven and nine years, 17 00:00:47,881 --> 00:00:52,886 and all of them underwent a lung MRI and a pulmonary function test. 18 00:00:53,511 --> 00:00:57,474 What we found was that we could detect structural lung abnormalities 19 00:00:57,474 --> 00:00:59,142 that were more present in the children 20 00:00:59,142 --> 00:01:02,312 who had a history of BPD compared to those who did not. 21 00:01:03,104 --> 00:01:07,108 We also, as part of this study, looked at differences in physical activity 22 00:01:07,108 --> 00:01:10,653 and sleep patterns between children who had a history of BPD 23 00:01:10,779 --> 00:01:12,989 and those who didn't and found no differences. 24 00:01:13,948 --> 00:01:14,991 The next steps for 25 00:01:14,991 --> 00:01:18,411 this research are going to be to embark on a larger CIHR 26 00:01:18,745 --> 00:01:22,415 funded study that's going to be carried out at four centers across Canada. 27 00:01:22,916 --> 00:01:25,585 In this study, we're going to be looking at MRI 28 00:01:25,585 --> 00:01:29,089 of the lung in newborns who were born extremely preterm 29 00:01:29,464 --> 00:01:33,009 and determining if the findings on the MRI will help us 30 00:01:33,009 --> 00:01:36,346 predict their respiratory problems over the next two years of life.