Natural Evolution of Serum Antibodies in Children and Adults with SARS-CoV-2 and Household Contacts.


The study will include children and adults who have tested positive for COVID-19 along with their household members who may or may not have had known infection. All participants will have blood tests at 4 time-points over 12-months to look for antibodies specific to the virus causing COVID-19. All study participants will be informed of their antibody results. The study team is looking for 75 children and 125 adults who have had a known COVID-19 infection. They hope to enroll all members of a household but, at minimum, 2 members must enroll to be eligible.

This study will advance the understanding of how antibodies develop in response to COVID-19 infection. Antibodies may be a key element of protection to COVID-19 and will provide insight into how the virus spreads within households. The team has partnered with regional and provincial public health agencies. Results from this study will be essential to inform key decisions regarding the relaxation of physical distancing rules that impact children and their families.

For more information on the study, or if you are looking to enroll, please email [email protected]

Lead Researchers


  1. Maala Bhatt

    Investigator, CHEO Research Institute

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  2. Roger Zemek

    Senior Scientist, CHEO Research Institute

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